IBD Status Applet

Java 1.6 required

Java 1.6 required

This applet takes as input the breakpoint analysis data (Nature Dib et al.(1996);380:152-154) from the 'Fondation Jean-Dausset' (CEPH) and display the Identical By Descent (IBD) regions between a pair of related individuals. Two people share an allele identical by descent if the two copies of the allele were inherited from a common ancestor. A pair of siblings can share 0, 1, or 2 alleles:

• 0: not the same alleles
• 1: only one allele in common
• 2: both same alleles

As an example, this IBD status can be used to design the controls of a CGH assay.

• Top left pane: a linkage table with genotype=f(individual,marker)
• Middle left pane: the list of individual. Using the Ctrl-key, select two related individuals an press the Add sib button. Your new pair is added in the bottom left table.
• Bottom left pane: the list of sib-pairs: for each pair, the IBD status is displayed in the right table
• Right table:
  • Marker index
  • chromosome
  • STS D-Number
  • Start-position (build 36)
  • End-position (build 36)
  • IBD status of each sib-pair(if any)
  • Count IBD with unknown status
  • Count IBD. 0
  • Count IBD. 1
  • Count IBD. 2

I wrote this software a few monthes ago but it was not much used, so I was given the permission to release this version to the community. There is no warranty of any kind for this program. Enjoy.